Para andar, faça um farmacológico?!?!?

Tissue Doppler systolic velocity change during dobutamine stress echocardiography predicts contractile reserve and exercise tolerance in patients with heart failureClique para ler o artigo.

Methods and results Sixty-four HF patients (age 67 ± 9 years, 58% with an ischaemic aetiology, and a mean value of the ejection fraction 29 ± 7%) underwent high-dose DSE.The patient population was divided into two groups: with rest–stress Sm change during DSE ≤ 2.02 cm/s and with rest–stress Sm change >2.02 cm/s. Patients with Sm rest–stress >2.02 change during DSE, compared with patients with rest–stress change ≤2.02, showed a lower incidence of severe diastolic dysfunction at rest (16 vs. 46%, P= 0.039) and lower E/Ea values (11 ± 5 vs. 15 ± 6, P = 0.005), similar ejection fraction at rest but higher ejection fraction at peak DSE (53 ± 14 vs. 41 ± 12%, P = 0.001), better myocardial contractile reserve assessed by a pressure–volume relationship (1.89 ± 2.01 vs. 0.58 ± 1.38 mmHg/mL/m2, P = 0.004), with a lower end-systolic volume (−46 ± 20 vs. −24 ± 19%, P< 0.001), a higher increase in the ejection fraction (23 ± 10 vs. 12 ± 10%, P = 0.001) during DSE, and better peak oxygen consumption (16 ± 4 vs. 13 ± 2 mL/kg/min, P = 0.01).

Conclusion In patients with HF, the rest–stress variation of mitral annulus systolic velocities during DSE predicts the presence of myocardial contractile reserve and exercise tolerance.

Fazer pesquisa é um grande mérito para qualquer equipe. Mas para testar capacidade de exercício em cardiopatas, é melhor pedalar ou caminhar.

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