Observational studies of necrotic core progression identify intraplaque hemorrhage as a critical factor in atherosclerotic plaque growth and destabilization…………………………………………………………..Neoangiogenesis is closely associated with plaque progression and is likely the primary source of intraplaque hemorrhage at sites of microvessel incompetence…………………………………………………..This process initiates leakage of RBCs into the plaque and induces a cycle of inflammation and neovascularization. 
Aqui artigo completo. 
………………………………..É interessante notar que o colesterol vem da vasa vasorum e mais, uma fonte importante de colesterol é a angiongênese com as hemorragias intra placas.
