Microbolhas na era pós Covid

https://doi.org/10.1016/j.echo.2023.10.010

Conclusion

Our data indicate that back pain or headache, typically self-limiting and not requiring treatment, is a more common side effect of Definity and is less common when administered by steady-state infusion compared with bolus administration. Other ADRs, including severe ADR by our definition with cardiopulmonary involvement, are more common with Lumason and occur at a rate of 8.5 per 10,000 administrations, which is approximately 7-fold higher than with Definity. While still rare, most concerning