Dia: 10 de agosto de 2011

Coronary Artery Plaque Burden Does Not Affect Left Ventricular Diastolic Function in Asymptomatic Adults with Normal Ejection Fraction
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Journal of the American Society of Echocardiography
Issue: Volume 24(8), August 2011, p 909–914
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Background:: Coronary artery disease (CAD) is commonly cited as a mechanism underlying diastolic dysfunction. However, the association of CAD without ischemia and left ventricular (LV) diastolic dysfunction has not been convincingly demonstrated in asymptomatic patients. The objective of this study was to determine if such a relation exists using coronary artery calcium score (CACS) as a surrogate for coronary atherosclerosis burden.
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Conclusions:: In asymptomatic patients with normal LV ejection fraction and negative cardiac stress test results, CACS does not correlate with LV diastolic function as defined by established Doppler echocardiographic criteria. In the absence of ischemia, postinfarction LV remodeling, or previous coronary artery bypass surgery, CAD does not appear be a cause of LV diastolic dysfunction in asymptomatic patients.
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Carotid Artery Stiffness and Diastolic Function in Subjects without Known Cardiovascular Disease
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Journal of the American Society of Echocardiography
Issue: Volume 24(8), August 2011, p 915–921
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Background:: The aim of this study was to investigate the relationship between carotid artery stiffness and diastolic function in a cohort of subjects without known cardiovascular risk factors and/or overt cardiovascular disease
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Results:: Stiffness parameter and Ep were correlated inversely with transmitral E wave (P < .01), E/A ratio, and septal Em (P < .01) and positively with A wave (P < .001). IMT was also associated with A wave, E/A ratio, Em, and Am but not with E wave. The correlation between arterial stiffness and left ventricular diastolic function remained significant after multivariate adjustment for age, sex, pulse pressure, and body mass index, but not with IMT.
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Parâmetros de elasticidade da Carótida se correlacionam com a função diastólica, sugerindo uma relação íntima da circulação central e periférica.
Mais uma evidência da doença arterial como patologia do corpo inteiro e não limitada a placas.
Conceito óbvio mas ignorado no diagnóstico e tratamento do risco cardiovascular.
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Na oclusão da carótida comum (unilateralmente), vemos um fluxo retrógrado vindo pela externa, que tem comunicação com as artérias contra-laterais pelos seus ramos.