1. Susan J. Zieman,
2. Vojtech Melenovsky,
3. David A. Kass

–Author Affiliations

1. 
   
   From the Department of Medicine (S.J.Z., V.M., D.A.K.), Gerontology Research Center (V.M.), Cardiology Division, National Institute on Aging, Johns Hopkins Medical Institutions, Baltimore, Md.

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http://atvb.ahajournals.org/content/25/5/932.full

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The growing prevalence and associated risk of arterial stiffness provide a major thrust to better understand the underlying molecular, cellular, and genetic causes and the resultant physiological impact of this condition. Reduction of arterial stiffness of these larger vessels will likely have a significant impact on morbidity and mortality of older adults, as well as diabetic subjects and those with chronic renal disease, and will likely improve quality of life in these populations.

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Apesar do tratamento em cardiologia ser “placacentrico”, ela não representa a patologia cardiovascular por completo. Alterações precoces no Stiffness podem ter consequências ainda não conhecidas. A própria rutura da placa deve está relacionada a fatores mecânicos, principalmente no idoso.

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