Impaired LA blood flow has been implicated as a source for intra-atrial thrombus formation and, thus, risk for thromboembolism in patients with AF.
Given that thrombus formation occurs predominantly in the LAA, it is thought that abnormal flow, such as reduced peak velocity and elevated stasis, at this location contributes to increased risk for stroke.
This 4D flow MRI study delineated LA and LAA flow dynamics in normal controls and patients with AF.
Although LAA flow velocities were clearly lower than LA flow velocities in controls, there appeared to be a more complex relationship of flow between the LA and LAA in patients with AF, suggesting that the atrial myopathy underlying AF affects global LA and LAA flow, resulting in an overall reduction in the regional difference noted in controls.
Os trombos preferem o apêndice atrial.
Estudo com TEE e RM mostra diferentes velocidades e estases no átrio e no apêndice.
Com a FA, essas diferenças diminuem.
Estudo muito interessante. Mostra influencia da idade e da anatomia nas modificações.