
| Atrial functional MR typically occurs in the context of AF and/or HFpEF. | |
| Isolated annular dilation, insufficient leaflet growth, and impaired annular dynamics are mechanical culprits. | |
| • | Early discrimination between atrial functional MR and secondary MR is pivotal to accommodate for different therapeutic needs. |
| • | Further study is needed to clarify the impact of early rhythm restoration strategies and mitral annular interventions to treat atrial functional MR. |
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