| Atrial functional MR typically occurs in the context of AF and/or HFpEF. |
| Isolated annular dilation, insufficient leaflet growth, and impaired annular dynamics are mechanical culprits. |
| • | Early discrimination between atrial functional MR and secondary MR is pivotal to accommodate for different therapeutic needs. |
| • | Further study is needed to clarify the impact of early rhythm restoration strategies and mitral annular interventions to treat atrial functional MR. |
https://www.jacc.org/doi/abs/10.1016/j.jacc.2019.02.061#:~:text=Highlights,-%E2%80%A2&text=Atrial%20functional%20MR%20typically%20occurs,of%20AF%20and%2For%20HFpEF.&text=Isolated%20annular%20dilation%2C%20insufficient%20leaflet,annular%20dynamics%20are%20mechanical%20culprits.&text=Early%20discrimination%20between%20atrial%20functional,accommodate%20for%20different%20therapeutic%20needs
