Doenças congênitas que encontramos nos adultos

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http://circ.ahajournals.org/content/114/22/2412.full

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Left ventricular outflow tract obstructions (LVOTOs) encompass a series of stenotic lesions starting in the anatomic left ventricular outflow tract (LVOT) and stretching to the descending portion of the aortic arch Obstruction may be subvalvar, valvar, or supravalvar. These obstructions to forward flow may present alone or in concert, as in the frequent association of a bicuspid aortic valve with coarctation of the aorta.

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Brilhante revisão de obstruções ao trabalho de ejeção do ventrículo esquerdo.

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Arterial Stiffness: Uma saída para a ecocardiografia?

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http://content.onlinejacc.org/article.aspx?articleid=1144323

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The 2007 European guidelines for the management of hypertension and guidelines for CVD prevention in clinical practice recommend, given all the aforementioned, aortic PWV as a test to assess target organ damage.

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Todos os ecocardiografistas já fazem Doppler de Carótidas, ou deveriam.

Esses podem oferecer o marcador de risco medido com a IMT.

Mas no exame de ecocardiografia existe um marcador vascular de risco que pode virar uma ferramenta de diagnóstico e prevenção. 

Inclusive já é aceito em diretrizes de países desenvolvidos.

Avaliação da Aorta não serve só para descartar Aneurisma!!!!

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Therapy of Arterial Stiffness: O que você deveria saber

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Mechanisms, Pathophysiology, and Therapy of Arterial Stiffness

  1. Susan J. Zieman,
  2. Vojtech Melenovsky,
  3. David A. Kass

–Author Affiliations


  1. From the Department of Medicine (S.J.Z., V.M., D.A.K.), Gerontology Research Center (V.M.), Cardiology Division, National Institute on Aging, Johns Hopkins Medical Institutions, Baltimore, Md.

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http://atvb.ahajournals.org/content/25/5/932.full

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The growing prevalence and associated risk of arterial stiffness provide a major thrust to better understand the underlying molecular, cellular, and genetic causes and the resultant physiological impact of this condition. Reduction of arterial stiffness of these larger vessels will likely have a significant impact on morbidity and mortality of older adults, as well as diabetic subjects and those with chronic renal disease, and will likely improve quality of life in these populations.

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Apesar do tratamento em cardiologia ser “placacentrico”, ela não representa a patologia cardiovascular por completo. Alterações precoces no Stiffness podem ter consequências ainda não conhecidas. A própria rutura da placa deve está relacionada a fatores mecânicos, principalmente no idoso.

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Vale a pena procurar isquemia coronária no DM assintomático?

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Conclusions  High-risk asymptomatic patients with DM and normal MPS (78%) have a low rate of first manifestations of CAD. Patients with abnormal MPS at baseline (22%) have a 7-fold higher rate of progression to “overt or silent CAD,” despite therapy. Randomized patients’ outcomes suggest that a combined invasive and medical strategy for silent CAD may reduce scintigraphic but not symptomatic CAD progression versus medical therapy alone.

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http://imaging.onlinejacc.org/article.aspx?articleID=1905468

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O que o editorial aponta:

In BARDOT, those treated conservatively had considerably lower rates of antiplatelet agents and statins prescribed; hence, there appears to be an opportunity to optimize medical therapy in those with normal nuclear stress tests..

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http://imaging.onlinejacc.org/article.aspx?articleid=1913659

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Veja abaixo outro estudo com ecocardiograma:

http://echotalkblog.com/2008/06/10/stress-echocardiography-in-diabetes-mellitus/

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Veja abaixo que o ecoestresse é o único exame com boa relação custo-benefício:

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http://echotalkblog.com/2007/08/06/para-diabetes-ecostress/