Dia: 18 de outubro de 2014

http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00090/full

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During Exercise

During exercise E_A has been shown to increase (Najjar et al., 2004; Otsuki et al., 2006), decline (Asanoi et al., 1992), or remain unchanged (Cohen-Solal et al., 1998). The response of E_A during exercise is dependent on the changes in its components and has important consequences on the Frank–Starling mechanism (Chantler et al., 2011). E_A is linearly related to heart rate and peripheral resistance, and inversely related to compliance (Segers et al., 2002; Chemla et al., 2003, Otsuki et al., 2006; Chantler et al., 2011). Both resistance and compliance usually decrease during exercise (reflecting less resistance to blood flow in the microcirculation, but increased stiffness of the conduit arteries) and the relative contribution of the pulsatile component (compliance) to E_A increases, so that by 80% of peak exercise the resistive and the pulsatile components provide nearly equal contributions to E_A (Otsuki et al., 2006). With advancing age, the ability to increase heart rate, and lower resistance during exercise is blunted.

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Envelhecimento e sua relação com a diástole passa pela resistência periférica. Está aqui a explicação para os falso doentes da diástole e verdadeiros doentes da resistência periférica?

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http://www.wikiecho.org/wiki/Arterial-ventricular_coupling_evaluation_by_echocardiography

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No WIKIECHO ficou resumido.

Abaixo o texto completo

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http://jap.physiology.org/content/105/4/1342

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CONCLUSIONS

Examination of the alterations in E_A/E_LV and its components, E_A and E_LV with aging, hypertension, and HF at rest and during exercise is often overlooked, yet it can yield mechanistic insights into the pathophysiology of these conditions and how they differ between men and women.