Conclusions The authors describe a “malignant” subset of patients with MVP who experienced life-threatening ventricular arrhythmias. This phenotype is characterized by bileaflet MVP, female sex, and frequent complex ventricular ectopic activity, including premature ventricular contractions of the outflow tract alternating with papillary muscle or fascicular origin.
In this young cohort of survivors with documented OHCA( out-of-hospital cardiac arrest ), we identified a potentially “malignant” MVP–ventricular arrhythmia phenotype. It is characterized by young women with bileaflet MVP, biphasic or inverted T waves in the inferior leads, and frequent complex ventricular ectopic activity with documented ventricular bigeminy or VT as well as PVC configurations of outflow tract alternating with papillary muscle or fascicular origin. A new approach to prospectively identify this “malignant” subset of patients is warranted.
Estes casos estão nos laboratórios de ecocardiografia de todo o mundo, sem uma aprofundação na investigação.