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Left ventricular (LV) short-axis views at the apical, mid, and basal levels, and LV apical four, two and three-chamber views were acquired, using a frame rate >44 frames/sec. At each plane, 3 consecutive cardiac cycles were obtained at end-expiration breath holding and stored digitally for offline analysis. Image analysis was performed off line on a PC workstation using custom analysis software (Echopac PC, Version 7.0.X; GE Healthcare, Fairfield, CT, USA). Color tissue Doppler was measured off-line at the septal and lateral mitral valve annulus, e′ waves were obtained. The mean value of the septal and lateral e′ was used to calculate the E/e′ ratio.
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Conclusion
In a subgroup of asymptomatic patients with Chagas’ disease without evident cardiac involvement, 2D strain was reduced compared with healthy individuals, suggesting incipient LV dysfunction in these patients. 2D ST strain has the potential for detecting early myocardial impairment in the setting of Chagas’ disease.
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Marcação com Speckle Tracking revelou alterações em alguns segmentos de pacientes chagásicos.
Seria um marcador fino de alterações da doença no miocárdio antes de afetar a condução ou concomitantes com as alterações elétricas?
Chagas continua sendo um mistério em sua fisiopatologia.
Estudo elegante e instigante.
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